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Profile of Ashfaque  Hossain
   
 
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Profile created on 05/02/2007

 

M.Sc.: Microbiology, University of Dhaka

Ph.D.: Microbiology, University of Glasgow, U.K.

Post Doctorate: University of Nebraska, Lincoln and Harvard Medical School, Boston, USA

Present Position: Senior Scientist, Molecular Biology, Creighton University School of Medicine, Omaha, NE, USA

E-mail: ashfaquehossain@yahoo.com

Achievement : ·Contributed significantly to the understanding of the molecular mechanism of interaction of Herpes Virus with mammalian cell cycle machinery. The results were published in high impact virology journals. ·Developed a technology for rapid isolation of high quality RNA from gram-positive and gram-negative clinical isolates for gene expression studies (patent pending). California based biotechnology company Invitrogen developed a kit based upon this technology and the kit is in the market since 2004. Founder and Present President of DUMAA (Dhaka University Microbiology Alumni Association). Prime mover in creating Dhaka University Microbiology Endowment Fund in 2005 through DUMAA by successfully carrying out an online fund raising drive and collecting donations from DU Microbiology alumni from different countries of the world. This is first Department- based endowment fund ever created in Bangladesh.

Future Plan : To establish a Biotechnology Company in the USA with a subsidiary in Bangladesh.

Research Interest : Molecular and Cellular Microbiology of host pathogen interaction. Development of rapid diagnostic methods for detection of infectious diseases.

Latest Publications :

     Hanson, N.D., Hossain, A. Buck, A. Moland, E.S. and Thomson, K.S. (2006) The First Occurrence of a Pseudomonas aeruginosa in the United States Producing an IMP Metallo-β-lactamase, IMP-18. Antimicrobial Agents and Chemotherapy 50: 1272-2273.

     Hossain, A, Ferraro,M. J., Pino. R. M., Dew, R. B. III, Moland, E.S., Lockhart, T. J., Thomson, K. S. Goering, R. V. and Hanson, N.D. (2004) Plasmid-mediated Carbapenem hydrolyzing enzyme, KPC-2, in Enterobacter sp. Antimicrobial Agents and Chemotherapy 48: 4438-4440

     Hossain, A. Reisbig, M.D. and Hanson, N.D. (2004) Plasmid-encoded functions compensate for the biological cost of AmpC over-expression in a clinical isolate of Salmonella typhimurium. J. Antimicrobial Chemotherapy 53: 964-970.

     Jiang, Y., Hossain, A., Winkler, M. T., Holt, T., Doster, A. and Jones, C. (1998) A protein encoded by the latency- related gene of bovine herpes virus 1 is expressed in trigeminal ganglionic neuron of latently infected cattle and interacts with cyclin dependent kinase 2 during productive infection. J. Virology 72: 8133-8142.

     Hossain, A., Holt, T. Zanella, J. and Jones, C. (1997) Analysis of cyclin dependent kinase activity after herpes simplex virus type 2 infection. J. General Virology 78, 3341-3348.